Selected Publications
Divergent Residues Within Histone H3 Dictate a Unique Chromatin Structure in Saccharomyces cerevisiae. McBurney KL, Leung A, Choi JK, Martin BJ, Irwin NA, Bartke T, Nelson CJ, Howe LJ. Genetics. (2016). 202:341-9.
Polarization of the endoplasmic reticulum by ER-septin tethering. Chao JT, Wong AK, Tavassoli S, Young BP, Chruscicki A, Fang NN, Howe LJ, Mayor T, Foster LJ, Loewen CJ. Cell. (2014). 158:620-32.
Histone H3K4 demethylation is negatively regulated by histone H3 acetylation in Saccharomyces cerevisiae. Maltby VE, Martin BJ, Brind’Amour J, Chruscicki AT, McBurney KL, Schulze JM, Johnson IJ, Hills M, Hentrich T, Kobor MS, Lorincz MC, Howe LJ. Proc Natl Acad Sci U S A. (2012). 109:18505-10.
Histone H3 lysine 36 methylation targets the Isw1b remodeling complex to chromatin. Maltby, V.E., Martin, B.J., Schulze, J.M., Johnson, I., Hentrich, T., Sharma, A., Kobor, M.S., Howe, L. Mol. Cell. Biol. (2012). 32:3479-85.
Critical Determinants for Chromatin Binding by Saccharomyces cerevisiae Yng1 Exist Outside of the PHD Finger. Chruscicki, A.T., Macdonald, V.E., Young, B.P., Loewen, C.J., and Howe LJ. Genetics (2010). 185:469-77.
Histone acetylation: where to go and how to get there. MacDonald VE, Howe LJ. Epigenetics. (2009). 4:139-43.
Choi, J.K., and L. Howe. (2009) Histone acetylation – truth of consequences? BIOCHEMISTRY AND CELL BIOLOGY. 87:139-150.
Acetylation of Rsc4p by Gcn5p is essential in the absence of histone H3 acetylation. Choi, J.K., D.E. Grimes, K. Rowe, and L. Howe. Mol. Cell. Biol. 28: 6967-6972 (2008).
Proteome-wide analysis in Saccharomyces cerevisiae identifies several PHD fingers as novel direct and selective binding modules of histone H3 methylated at either lysine 4 or lysine 36. Shi, X., I. Kachirskaia, K.L. Walter, J.H. Kuo, A. Lake, F. Davrazou, S.M. Chan, D.E.G. Martin, I.M. Fingerman, S.D. Briggs, L. Howe, P.J. Utz, T.G. Kutateladze, A.A. Lugovskoy, M.T. Bedford, and O. Gozani. J. Biol. Chem . 282 :2450-5 (2007)
The Yng1p plant homeodomain finger is a methyl-histone binding module that recognizes lysine 4-methylated histone H3. Martin, D.E.G., K. Baetz, X. Shi, K.L. Walter, V.E. MacDonald, M.J. Wlodarski, O. Gozani, P. Hieter, and L. Howe.
Mol. Cell. Biol . 26 :7871-9 (2006)
Methylation of Histone H3 Mediates the Association of the NuA3 Histone Acetyltransferase with Chromatin Martin, D.E.G., D.E. Grimes, K. Baetz, and L. Howe. Mol. Cell. Biol . 26 : 3018 – 3028 (2006)
