Lefebvre Lab projects

Plain English (with a québécois accent…)
Therian mammals contain some strange genes which are only expressed from the maternally or only the paternally inherited chromosome. These are called imprinted genes. In humans, abnormal expression of imprinted genes is associated with a number of rare syndromes. We still know very little about imprinted genes, why they are imprinted and what their functions are in mammalian biology. Work in my laboratory at UBC uses the mouse as a model organism to study the function and mechanism of genomic imprinting during mammalian development.
(For the québécois version, delete all the H’s at the beginning of words, or following T’s. Strangely enough, THE is pronounced DE in Québec…)

a place of mind, The University of British Columbia

Molecular Epigenetics
2350 Health Sciences Mall,
Vancouver, BC, V6T 1Z3, Canada

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